Chemodex

o-Cresolphthalein Complexone

Product Code:
 
CDX-C0850
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +20°C. Long term: +20°C
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Chemical Structure

Chemical Structure

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CDX-C0850-G0055 g£57.00
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CDX-C0850-G01010 g£92.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
o-CPC; o-Cresolphthalein-3',3''-bis-methyleneiminodiacetic acid; o-Cresolphthalexon; Metal phthalein; Phthalein purple; Xylenylphthalein-bisiminodiacetic acid
Appearance:
Off-white crystalline powder.
CAS:
2411-89-4
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)
InChiKey:
IYZPEGVSBUNMBE-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 2411-89-4. Formula: C32H32N2O12. MW: 636.6. o-Cresolphthalein Complexone is a pH indicator dye that is colorless at pH 8.2 and red at pH 9.8 and commonly used for the colorimetric determination of calcium. Spectral data: UV-Visible (lambdamax) 577-580 nm in 0.1 M NaOH. o-CPC is used for automated determination of calcium in serum and plasma, as well as in other biological fluids. o-CPC works by forming a complex with calcium ions in an alkaline solution. The complex is purple in color, and the intensity of the color is proportional to the concentration of calcium ions in the solution. This makes o-CPC a useful tool for measuring calcium levels in serum. o-CPC has also been used as an alkaline earth metal ion indicator and in the synthesis of some polymers. o-Cresolphthalein Complexone (o-CPC) is an indicator in complexometric titrations. Complexometric titrations involve the titration of metal ions with a chelating agent, and o-CPC is a post-column reagent (PCR) often used to detect the endpoint of the titration. In the presence of metal ions, particularly divalent metal ions such as calcium (Ca2+) and magnesium (Mg2+), o-CPC forms stable complexes with these ions. The color change of the complex is used to signal the endpoint of the titration. o-CPC is often used as analytic reagent for detection of trace chemicals (e.g. in water analysis).
MDL:
MFCD00005911
Molecular Formula:
C32H32N2O12
Molecular Weight:
636.6
Package Type:
Vial
Product Description:
o-Cresolphthalein Complexone is a pH indicator dye that is colorless at pH 8.2 and red at pH 9.8 and commonly used for the colorimetric determination of calcium. Spectral data: UV-Visible (lambdamax) 577-580 nm in 0.1 M NaOH. o-CPC is used for automated determination of calcium in serum and plasma, as well as in other biological fluids. o-CPC works by forming a complex with calcium ions in an alkaline solution. The complex is purple in color, and the intensity of the color is proportional to the concentration of calcium ions in the solution. This makes o-CPC a useful tool for measuring calcium levels in serum. o-CPC has also been used as an alkaline earth metal ion indicator and in the synthesis of some polymers. o-Cresolphthalein Complexone (o-CPC) is an indicator in complexometric titrations. Complexometric titrations involve the titration of metal ions with a chelating agent, and o-CPC is a post-column reagent (PCR) often used to detect the endpoint of the titration. In the presence of metal ions, particularly divalent metal ions such as calcium (Ca2+) and magnesium (Mg2+), o-CPC forms stable complexes with these ions. The color change of the complex is used to signal the endpoint of the titration. o-CPC is often used as analytic reagent for detection of trace chemicals (e.g. in water analysis).
Purity:
>80% (Dye content)
SMILES:
O=C1OC(C=2C1=CC=CC2)(C3=CC(CN(CC(O)=O)CC(O)=O)=C(O)C(C)=C3)C4=CC(CN(CC(O)=O)CC(O)=O)=C(O)C(C)=C4
Solubility Chemicals:
Soluble in methanol or ethanol. Slightly soluble in water (1mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.

Documents

References

(1) L.G. Morin; Am. J. Clin. Pathol. 61, 114 (1974) | (2) A. Hitchen & G. Zechanowitsch; Talanta 27, 269 (1980) | (3) W. Bashir & B. Paull; J. Chromatogr. A 907, 191 (2001) | (4) H. Nikawa; Mycoses 46, 471 (2003) | (5) Z.O. Tesfaldet, et al.; Talanta 64, 981 (2004) | (6) R.W. Sabnis; Handbook of Acid-Base Indicators (2008) | (7) A. Duran, et al.; J. Hazard Mater. 169, 466 (2009) | (8) S.A. Banihani, et al.; J. Basic. Clin. Physiol. Pharmacol. 26, 141 (2015) | (9) J.J. Manoranjitham & S.S. Narayanan; Food Chem. 342, 128246 (2021)