1-Hydroxyibuprofen
Product Code:
CDX-H0943
CDX-H0943
Regulatory Status:
RUO
RUO
Shipping:
Ambient
Ambient
Storage:
Short term: +4°C. Long term: -20°C
Short term: +4°C. Long term: -20°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-H0943-M010 | 10 mg | £103.00 |
Quantity:
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
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Further Information
Alternate Names/Synonyms:
Ibuprofen Impurity L; Ibuprofen EP Impurity L; 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic acid; 1-OH IBU
Appearance:
White to off-white powder or crystals.
CAS:
53949-53-4
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C13H18O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9,12,14H,1-3H3,(H,15,16)
InChiKey:
RMOQYHYFRKTDRI-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 53949-53-4. Formula: C13H18O3. MW: 222.28. The metabolite 1-Hydroxyibuprofen (Ibuprofen Impurity L) is a degradation product of Ibuprofen which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain from various conditions such as headache, dental pain or menstrual cramps. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2. Ibuprofen is metabolized in the human liver to a number of metabolites including 1-hydroxyibuprofen (1-OH-Ibu), 2-OH-Ibu and 3-OH-Ibu, respectively. 1-Hydroxyibuprofen was determined as the dominant compound in soils. This product can be used as a working standard or secondary analytical reference standard.
MDL:
MFCD08275586
Molecular Formula:
C13H18O3
Molecular Weight:
222.28
Package Type:
Vial
Precautions:
P264 - P270 - P301 + P312 - P501
Product Description:
The metabolite 1-Hydroxyibuprofen (Ibuprofen Impurity L) is a degradation product of Ibuprofen which is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain from various conditions such as headache, dental pain or menstrual cramps. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2. Ibuprofen is metabolized in the human liver to a number of metabolites including 1-hydroxyibuprofen (1-OH-Ibu), 2-OH-Ibu and 3-OH-Ibu, respectively. 1-Hydroxyibuprofen was determined as the dominant compound in soils. This product can be used as a working standard or secondary analytical reference standard.
Purity:
>98% (HPLC)
Signal Word:
Warning
SMILES:
CC(C)C(O)c1ccc(cc1)C(C)C(O)=O
Solubility Chemicals:
Soluble in DMSO, DMF, ethanol or methanol (all 10mg/ml). Insoluble in water.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Documents
References
(1) I. Neunzig, et al.; J. Biotechnol. 157, 417 (2012) | (2) Z. Han, et al.; Chromatographia 80, 1353 (2017) | (3) E. Waraksa, et al.; J. Pharm. Biomed. Anal. 152, 279 (2018) | (4) T. Dolu & B. Nas; Environ. Res. 227, 115731 (2023)